Corporate Profile

We are a clinical-stage biotechnology company developing therapeutics that are designed to target the biological processes that lie at the heart of fibrosis and impact a broad range of fibrotic and related diseases, including cancer. Our initial focus is on the development of small-molecule inhibitors of galectin-3 and lysyl oxidase-like 2, or LOXL2, which play key roles in regulating fibrosis. We believe our product candidates are distinct from the current generation of antifibrotic agents and have the potential to significantly improve patientsā€™ clinical outcomes and enhance their quality of life.

Our lead product candidate is an inhaled galectin-3 modulator, GB0139, currently in a Phase 2b study for the treatment of idiopathic pulmonary fibrosis. Our pipeline also includes an orally active galectin-3 inhibitor, GB1211, that is expected to be part of (i) a phase 2 trial for the potential treatment of NSCLC in combination with an anti-PD1/-L1 product and (ii) a phase 1b/2a trial in liver cirrhosis, as well as an orally active LOXL2 inhibitor, GB2064, that is part of an ongoing phase 2 trial for the potential treatment of myelofibrosis.

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News Releases

07 Dec '22
Intermediate assessment of GB2064 in the Phase 2 myelofibrosis trial showed target engagement in the bone marrow and reduction in collagen fibrosis in four out of five evaluable patients GB2064 is an oral inhibitor of the collagen cross-linking enzyme LOXL-2, which is linked to myelofibrosis BOSTON
08 Nov '22
BOSTON , Nov. 08, 2022 (GLOBE NEWSWIRE) -- Galecto, Inc. (NASDAQ: GLTO), a clinical-stage biotechnology company and a world leader in galectin biology focused on the development of novel treatments for fibrosis and cancer, today announced its operating and financial results for the quarter ended
08 Nov '22
Statistically significant reductions observed in ALT, AST and GGT, supporting further developmentĀ of GB1211 in severe liver diseases Findings to be discussed in a conference call and virtual webinar today, November 8, 2022 , at 8 a.m. ET BOSTON , Nov. 08, 2022 (GLOBE NEWSWIRE) -- Galecto, Inc.

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